Bioprocess considerations for production of secondary metabolites by plant cell suspension cultures

By S. Chattopadhyay, S. Farkya, A. Srivastava, Virendra S. Bisaria. 2002

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Application of an airlift bioreactor system for the production of adventitious root biomass and caffeic acid derivatives of Echinacea purpurea (2009, background): “The factors that influence effective oxygen transfer in plant cell cultures must be carefully analyzed when designing bioreactors for the production of metabolites [ 33 ].”
Production of secondary metabolites from cell and organ cultures: strategies and approaches for biomass improvement and metabolite accumulation (2014, background): “Aeration is another important factor that should be controlled in bioreactor cultures for optimization of biomass growth and secondary metabolite production (Chattopadhyay et al. 2002; Georgiev et al. 2009).”
Plant Tissue Culture: Current Status and Opportunities (2012, unknown): “Podophyllotoxin Podophyllum hexandrum [97]”