Recent Developments in Delivery, Bioavailability, Absorption and Metabolism of Curcumin: the Golden Pigment from Golden Spice

By S. Prasad, A. Tyagi, Bharat B. Aggarwal. Cancer research and treatment : official journal of Korean Cancer Association, 2014

1,017 citations recorded by the source corpus.

Curcumin (diferuloylmethane) is a yellow pigment present in the spice turmeric (Curcuma longa) that has been associated with antioxidant, anti-inflammatory, anticancer, antiviral, and antibacterial activities as indicated by over 6,000 citations. In addition, over one hundred clinical studies have been carried out with curcumin. One of the major problems with curcumin is perceived to be the bioavailability. How curcumin should be delivered in vivo, how bioavailable is it, how well curcumin is absorbed and how it is metabolized, is the focus of this review. Various formulations of curcumin that are currently available are also discussed.

Subfields: Biochemistry, Molecular Medicine, Pharmacology

View Paper: https://www.semanticscholar.org/paper/cb7cfd0acd26a5b07b7ee3a5022e1f83c81dfac6

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Citations in the corpus

• Bioactivity of dietary polyphenols: The role of metabolites (2020, background): “…curcumin analogs and the development of modified drugdelivery systems, including liposomal, nanoparticulated and phospholipid complex formulations of curcumin have also proved effectiveness in animal and human studies (Marczylo et al. 2007; Bisht and Maitra 2009; Prasad, Tyagi, and Aggarwal 2014).”
• The Chemistry of Curcumin: From Extraction to Therapeutic Agent (2014, neutral): “[96–98].”