Volume and number of neurons of the human hippocampal formation in normal aging and Alzheimer's disease

By G. Šimić, I. Kostović, Bengt Winblad, N. Bogdanovic. 1997

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Citations in the corpus

Human Hippocampal Neurogenesis Persists throughout Aging (2018, positive): “…GNs in anterior, mid, and posterior DG across ages agrees with earlier postmortem studies that used Hematoxylin/Eosin (Harding et al., 1998), Nissl (Simić et al., 1997), and Giemsa (West et al., 1994) stains and identified neurons solely based on morphology, finding age-related neuron loss in the…”
Automated Volumetry and Regional Thickness Analysis of Hippocampal Subfields and Medial Temporal Cortical Structures in Mild Cognitive Impairment (2014, background): “An additional motivation for more granular measurement of MTL cortical subregions is that the PRC and ERC are amongst the earliest sites of neurodegeneration in AD [Braak and Braak, 1995; Bobinski et al., 1997; Simić et al., 1997; West et al., 2004].”
Quantitative Comparison of 21 Protocols for Labeling Hippocampal Subfields and Parahippocampal Subregions in In Vivo MRI: Towards a Harmonized Segmentation Protocol (2015, background): “Different psychiatric and neurological disorders are known to affect hippocampal subfields and MTL cortical subregions differently, selectively, and in a complex progression (Braak & Braak, 1995; Arnold et al., 1995; Simić et al., 1997; de Lanerolle et al., 2003; West et al., 2004; Lucassen et al., ”
Dynamics of Gray Matter Loss in Alzheimer's Disease (2003, background): “In healthy aging, age-related neuronal loss does not occur in most regions of the neocortex (Terry et al., 1987; Morrison and Hof, 1997) and appears specific to the frontal cortex (de Brabander et al., 1998) and some hippocampal regions (e.g., CA1 and the subiculum) ( Simic et al., 1997 ).”
A computational atlas of the hippocampal formation using ex vivo, ultra-high resolution MRI: Application to adaptive segmentation of in vivo MRI (2015, unknown): “, 2014; Yassa and Stark, 2011), and to be affected differently by AD and normal aging — as indicated by ex vivo, histological studies (Braak and Braak, 1991; Braak and Braak, 1997; Arnold et al., 1991; Thal et al., 2000; Brady and Mufson, 1991; Simic et al., 1997; Harding et al., 1998).”
Variation in hippocampal neuron number with age and brain volume. (1998, methodology): “Table 3 Neuron number (×10 6 ) for each of the subregions of the hippocampus The effect of cerebral volume has not been considered in past analyses of age-related changes in CA1 neuron number (West and Gundersen, 1990; Simic et al., 1997).”
Adult Neurogenesis in Humans. (2015, background): “Stereological investigations of neuronal number in the adult human hippocampus have established that neuronal number declines with age, with neuronal number in the DG least affected (West and Gundersen 1990; West 1993; Simic et al. 1997; Harding et al. 1998; Korbo et al. 2004).”
Evolution of hippocampal shapes across the human lifespan (2013, background): “The inferior and superior views of the hippocampus are given on each panel. r 3082 r suggested significant age-associated neuronal loss in hippocampal subiculum and CA1 [Simic et al., 1997; West, 1993].”
Cytoarchitectonic mapping of the human amygdala, hippocampal region and entorhinal cortex: intersubject variability and probability maps (2005, background): “architecture and connectivity, but also by their vulnerability in age-related changes and neuropsychiatric disorders (Harding et al. 1998; Heimer 2000; Irwin et al. 2004; Simic et al. 1997; Narr et al. 2004).”