Dynamics of Gray Matter Loss in Alzheimer's Disease

By Paul M. Thompson, Kiralee M. Hayashi, G. D. de Zubicaray, Andrew L. Janke, Stephen E. Rose, J. Semple, D. Herman, Michael S. Hong, Stephanie S. Dittmer, D. Doddrell and 1 more. Journal of Neuroscience, 2003

1,211 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Psychiatry and Mental health, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/94eefd2472c56940cfc76a607cbc8eb4edc4e793

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Citations in the corpus

Automatic classification of patients with Alzheimer's disease from structural MRI: A comparison of ten methods using the ADNI database (2011, background): “Cortical thickness represents a direct index of atrophy and thus is a potentially powerful candidate to assist in the diagnosis of AD (Thompson et al., 2001, 2003, 2004; Lerch et al., 2005, 2008; Bakkour et al., 2009; Dickerson et al., 2009; Hua et al., 2009; McDonald et al., 2009).”
Permutation Tests for Classification: Towards Statistical Significance in Image-Based Studies (2003, methodology): “As we mentioned in the introduction, permutation tests have been used before in statistical studies of neuroanatomy and function [1,15,16].”
Insights into the ageing mind: a view from cognitive neuroscience (2004, background): “, although deterioration of the PFC is not observed early in the diseas”
Structural Abnormalities in the Brains of Human Subjects Who Use Methamphetamine (2004, methodology): “Cortical pattern matching The cortical pattern-matching approach used here (Thompson et al., 2003) has some strengths and weaknesses relative to voxelbased morphometry (VBM) (Ashburner and Friston, 1999, 2000; Salmond et al.”
The Brain's Default Network (2008, background): “Methods that survey atrophy across the brain in AD have also all converged to show disruption in the default network prominently including the medial temporal lobe (Scahill et al. 2002, Thompson et al. 2003, Buckner et al. 2005).”
Global and local gray matter loss in mild cognitive impairment and Alzheimer's disease (2004, background): “The right hemisphere has been described as having a btime lagQ in demonstrating atrophy (Thompson et al., 2003).”
A Network Diffusion Model of Disease Progression in Dementia (2012, positive): “The second-most persistent mode (Figures 2 and 4, top rows) closelyresemblestypicalAlzheimer’satrophyinmesialtemporal, posterior cingulate, and limbic structures, as well as lateral temporal and dorsolateral frontal cortex (Apostolova et al., 2007; Thompson et al., 2003).”
Open Access Series of Imaging Studies (OASIS): Longitudinal MRI Data in Nondemented and Demented Older Adults (2010, methodology): “Longitudinal analysis of measures derived from advanced computational methods, including nonlinear deformations and shape analysis, have also revealed ageand disease-associated changes in the brain (e.g., Buckner et al., 2005; Thompson et al., 2003;Wang et al., 2003; Scahill, Schott, Stevens, Rossor”
Molecular, Structural, and Functional Characterization of Alzheimer's Disease: Evidence for a Relationship between Default Activity, Amyloid, and Memory (2005, background): “Amyloid deposition correlates with atrophy and metabolism reduction in posterior cortical regions Atrophy was present in the precuneus at the earliest stages of conversion to AD and expanded to include more diffuse medial and lateral posterior parietal regions in very mild stages (Scahill et al., 20”
The Cortical Signature of Alzheimer's Disease: Regionally Specific Cortical Thinning Relates to Symptom Severity in Very Mild to Mild AD Dementia and is Detectable in Asymptomatic Amyloid-Positive Individuals (2008, methodology): “…the largest effects in temporal and parietal cortex (Karas et al. 2004; Du et al. 2007), with 15--20% thinning in caudal lateral temporal and posterior parietal cortex (Thompson et al. 2001, 2003; Lerch et al. 2005; Apostolova et al. 2007) as well as medial temporal cortex (Lerch et al. 2005).”
Tensor-Based Morphometry as a Neuroimaging Biomarker for Alzheimer’s Disease: An MRI Study of 676 AD, MCI, and Normal Subjects (2008, positive): “We computed the overall significance of group differences using permutation tests, corrected for multiple comparisons (Bullmore et al., 1999; Nichols and Holmes, 2002; Thompson et al., 2003; Chiang et al., 2007a; Chiang et al., 2007b).”
Mapping brain asymmetry (2003, background): “In Alzheimer's disease, a spreading wave of grey matter loss emerges initially in entorhinal and temporal–parietal cortices, sweeping into frontal and ultimately sensorimotor territory as the disease progresse”