Ten things you should know about transposable elements

By Guillaume Bourque, K. Burns, Mary Gehring, Vera Gorbunova, Andrei Seluanov, M. Hammell, Michael Imbeault, Z. Izsvák, H. Levin, T. Macfarlan and 2 more. Genome Biology, 2018

1,194 citations recorded by the source corpus.

Transposable elements (TEs) are major components of eukaryotic genomes. However, the extent of their impact on genome evolution, function, and disease remain a matter of intense interrogation. The rise of genomics and large-scale functional assays has shed new light on the multi-faceted activities of TEs and implies that they should no longer be marginalized. Here, we introduce the fundamental properties of TEs and their complex interactions with their cellular environment, which are crucial to understanding their impact and manifold consequences for organismal biology. While we draw examples primarily from mammalian systems, the core concepts outlined here are relevant to a broad range of organisms.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/ca9ba03e2e3c00a26c0a2e017cfefd48368079b2

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Citations in the corpus

RepeatModeler2 for automated genomic discovery of transposable element families (2020, background): “Within each class, TE sequences are extremely diverse and evolve rapidly (4, 10, 17).”
RepeatModeler2: automated genomic discovery of transposable element families (2019, background): “What makes TEs so potent in remodeling the genome but also challenging to annotate is their diversity in structures and sequences, which greatly vary across species (Huang et al. 2012; Bourque et al. 2018).”
Genetics and genomics of moso bamboo (Phyllostachys edulis): Current status, future challenges, and biotechnological opportunities toward a sustainable bamboo industry (2020, background): “Although their specific functions within the genome remain enigmatic, TEs are known to create spontaneous genomic variations by their transposition behavior (Bourque et al., 2018).”