In vivo demonstration that α-synuclein oligomers are toxic

By Beate Winner, R. Jappelli, S. Maji, Paula A. Desplats, Leah Boyer, S. Aigner, C. Hetzer, Thomas J. Loher, M. Vilar, Silvia Campioni and 9 more. Proceedings of the National Academy of Sciences of the United States of America, 2011

1,193 citations recorded by the source corpus.

Subfields: Neurology, Physiology

View Paper: https://www.semanticscholar.org/paper/ca87a1ffcf970f19f2718b2211d18883f5dd1cb3

Citations in the corpus

• α-Synuclein in Parkinson's disease. (2012, neutral): “Two major studies provided support to this idea, as they showed enhanced neurotoxicity both in cell culture and in vivo with artificial mutants of asynuclein that favored the formation of soluble oligomers over mature fibrils (Karpinar et al. 2009; Winner et al. 2011).”