Physicochemical Characteristics of Self-Assembled Nanoparticles Based on Glycol Chitosan Bearing 5β-Cholanic Acid

By Seunglee Kwon, J. Park, Hesson Chung, I. Kwon, S. Jeong, In‐San Kim. 2003

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Application of Light Scattering Techniques to Nanoparticle Characterization and Development (2018, background): “, 2007) and for other therapeutic purposes (Kwon et al., 2003; Park et al., 2004; Kim et al., 2006), the team was able to conjugate the peptide on the NP surface and detect the selective binding to atherosclerotic plaques in vivo, by adhering to the IL-4 receptor on endothelial cells, macrophages an”
Targeted delivery of low molecular drugs using chitosan and its derivatives. (2010, methodology): “developed hydrophobically modified glycol chitosans (HGCs) by covalent conjugation of bile acid (5β-cholanic acid or deoxycholic acid) to the backbone of glycol chitosan using carbodiimide chemistry [20,103].”