X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution

By C. Putnam, M. Hammel, Greg L. Hura, John A. Tainer. 2007

668 citations recorded by the source corpus.

Subfields: Materials Chemistry, Molecular Biology

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Citations in the corpus

The HDOCK server for integrated protein–protein docking (2020, background): “Third, the monodispersity will also be checked by comparing the MW from the SAXS data and the expected MW from the complex 108 .”
Iterative structure-based improvement of a respiratory syncytial virus fusion glycoprotein vaccine (2016, neutral): “In contrast, the sc9 Kratky plot plateaued near its maximum, consistent with a substantially flexible or unfolded molecule 42 .”
Combined sampler robot and high-performance liquid chromatography: a fully automated system for biological small-angle X-ray scattering experiments at the Synchrotron SOLEIL SWING beamline (2009, methodology): “Small angle X-ray scattering (SAXS) is the appropriate method to determine the size and shape of biological macromolecules and macromolecular complexes (Koch et al., 2003; Putnam et al., 2007).”
UCSF Chimera, MODELLER, and IMP: an Integrated Modeling System (2011, methodology): “SAXS proﬁles have been used widely for low-resolution structural characterization of molecules in solution (Petoukhov and Svergun, 2007; Putnam et al., 2007; Schneidman-Duhovny et al., 2010).”
Implementation and performance of SIBYLS: a dual endstation small-angle X-ray scattering and macromolecular crystallography beamline at the Advanced Light Source (2013, background): “46, 1–13 Scott Classen et al. SIBYLS beamline 9 structural information of the complete protein or complex, thus complementing partial high-resolution structural information from NMR or MX (Putnam et al., 2007).”
Structural Basis of RNA Recognition and Activation by Innate Immune Receptor RIG-I (2011, background): “The parabolic shape of the Kratky plot is lost and the peak amplitude decreases in the absence of RNA, indicative of greater flexibilit”