The olfactory bulbectomised rat as a model of depression.

By Cai Song, B. Leonard. Neuroscience and Biobehavioral Reviews, 2005

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Olfactory disorders and quality of life--an updated review. (2014, background): “2004; Song and Leonard 2005, for studies on rodents, and Deems et al.”
Depression: An Evolutionarily Conserved Mechanism to Terminate Separation Distress? A Review of Aminergic, Peptidergic, and Neural Network Perspectives (2009, background): “The olfactory bulb model indeed seems the furthest from human clinical concerns, but it is a robust depression analog in terms both of behavioral state and of response to chronic antidepressant administration (Cai & Leonard, 2006).”
Are The Dorsal and Ventral Hippocampus functionally distinct structures? (2010, background): “Such projections may play a role in the depression-like symptoms that follow loss of the olfactory bulb that are reversed by antidepressants and cannot be attributed to a loss in olfaction (Song and Leonard, 2005; Wang et al., 2007).”
Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models (2014, background): “…and AD and having a wide range of potentially applicable tools to study depression in animal models (Seligman et al., 1975; Jolly et al., 1999; Song and Leonard, 2005; Flint and Shifman, 2008; Nestler and Hyman, 2010), very little work has been devoted to determining the range of depressive…”