Oxidative stress and cancer: an overview.

By Venus Sosa, T. Moliné, R. Somoza, R. Paciucci, H. Kondoh, M. Lleonart. Ageing Research Reviews, 2013

1,312 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/c927872a3a933df8abcde637a476531f1f82d3ad

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. P. Lei
2. Carlotta Pucci
3. Gianni Ciofani
4. C. Martinelli
5. Qing-zhang Tuo

In Molecular Biology

1. M. Rodríguez‐Concepción
2. P. Lei
3. Carlotta Pucci
4. Gianni Ciofani
5. C. Martinelli
6. T. Vlachogianni
7. L. Zacarías
8. A. Valavanidis

Citations in the corpus

• Pulmonary Oxidative Stress, Inflammation and Cancer: Respirable Particulate Matter, Fibrous Dusts and Ozone as Major Causes of Lung Carcinogenesis through Reactive Oxygen Species Mechanisms (2013, background): “neoplasms, diabetes mellitus, atherosclerosis and various neurodegenerative diseases [24–28].”
• Oxidative Stress and Inflammation: What Polyphenols Can Do for Us? (2016, background): “Antioxidant properties of the polyphenolsmay be beneficial in the process of inflammation and in inflammation induced carcinogenesis [60, 61].”
• Innovative approaches for cancer treatment: current perspectives and new challenges (2019, background): “Oxidative stress and radical oxygen species are able to damage DNA (genetic alterations, DNA double strand breaks and chromosomal aberrations [95, 96]) and other biomacromolecules [97], such as lipids (membrane peroxidation and necrosis [98]) and proteins (significantly changing the regulation of tr”
• Ferroptosis: mechanisms and links with diseases (2021, background): “Cancer cells need a high metabolic rate to maintain their rapid proliferation, accompanied by an increase in ROS production.(173) Therefore, high ROS levels are an inherent feature of tumors, and cancer cells have to boost their antioxidant defense capacity to overcome this enhanced oxidative stress”
• Oxidative stress and reactive oxygen species in endothelial dysfunction associated with cardiovascular and metabolic diseases. (2018, background): “Elevated ROS levels have been involved in the onset of several diseases, including neurodegenerative disorders [8], cancer [9], renal diseases [10], pulmonary diseases [11], and metabolic diseases (e.”
• Extracellular matrix (ECM) stiffness and degradation as cancer drivers (2018, background): “Cancer cells also release reactive oxygen species to the TME for activation of these enzymes.(22)”
• A global perspective on carotenoids: Metabolism, biotechnology, and benefits for nutrition and health. (2018, background): “Increased ROS production can protect from cancer development by increasing the oxidative stress/damage response leading to apoptosis of the damaged cells [416].”
• Role of ROS and Nutritional Antioxidants in Human Diseases (2018, background): “In addition, cancer cells are characterized by more ROS production than normal cells due to an altered metabolism and increased energy demand (Sosa et al., 2013).”