Development and maturation of the immune system in zebrafish, Danio rerio: a gene expression profiling, in situ hybridization and immunological study.

By S. Lam, H. Chua, Z. Gong, T. Lam, Y. Sin. Developmental and Comparative Immunology, 2004

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Mucosal immunoglobulins and B cells of Teleost fish (2011, background): “H chain in pancreas (10 dpf), transcript of secretory Ig (13 dpf), transcript of Ig H chain in HK (19 dpf), and detectable humoral Ig (28 dpf), which was consistent with the time when carp plasma cells could be detected (4 wpf) (Danilova et al., 2005; Danilova and Steiner, 2002; Lam et al., 2004).”
Contribution of neutral processes to the assembly of gut microbial communities in the zebrafish over host development (2015, background): “…rRNA gene amplicon sequencing at important developmental milestones: 4 dpf (complete opening of the digestive tract), 10 dpf (after feeding began), 21, 28 and 35 dpf (activation of the adaptive immune system, Lam et al., 2004), 75 dpf (sexual maturity), and finally 380 dpf (onset of senescence).”
Ontogeny of the immune system of fish. (2006, methodology): “On the other hand, Danilova and Steiner [33] also using the WISH technique, observed Rag-1 expression in the zebrafish pancreas by day 4 and Lam and colleagues [19] by RT-PCR in 3 day-old zebrafish.”
Innate and adaptive immunity in teleost fish: a review. (2018, background): “In freshwater teleosts, the thymus is the first organ to become lymphoid, but before this event, the anterior kidney may contain hematopoietic progenitors, but not lymphocytes (Lam et al., 2004).”