More than just water channels: unexpected cellular roles of aquaporins

By A. Verkman. Journal of Cell Science, 2005

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Regulation of salivary gland function by autonomic nerves. (2007, background): “sweat glands and intestinal cells, is aquaporin independent but in tissues such as kidney and salivary gland, where fluid transport per unit surface area is much higher, aquaporins play a role (Verkman, 2005).”
Desalination by biomimetic aquaporin membranes: Review of status and prospects (2013, background): “AQP0, AQP4, and AqpZ), it is becoming increasingly clear that many aquaporins may have additional permeability properties [10].”
Astrocyte dysfunction in neurological disorders: a molecular perspective (2006, background): “Increasing evidence indicates that a coordinated action of both channels is required for the astrocytes to maintain K + and water homeostasis in the CN”
Biomimetic aquaporin membranes coming of age (2015, background): “Nontransporting functions for some aquaporins have also been suggested, such as cell–cell adhesion, membrane polarization, and regulation of interacting proteins, such as ion channels, for recent comprehensive reviews see [19,22].”