Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases.
By C. Zarow, S. Lyness, J. Mortimer, Helena Chui. Archives of Neurology, 2003
989 citations recorded by the source corpus.
Subfields: Neurology, Physiology, Psychiatry and Mental health
View Paper: https://www.semanticscholar.org/paper/c8801d2a26c226cdf7cbe3fe2033232a22683557
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Neurology
- K. Del Tredici
- H. Braak
- M. O’Banion
- A. Schapira
- Jose A. Obeso
- Michael T. Heneka
- M. Farrer
- Dennis W. Dickson
In Physiology
- K. Del Tredici
- H. Braak
- M. O’Banion
- Michael T. Heneka
- M. Farrer
- Dennis W. Dickson
- John Hardy
- John Q. Trojanowski
In Psychiatry and Mental health
- K. Del Tredici
- M. O’Banion
- H. Braak
- Michael T. Heneka
- M. Farrer
- John Hardy
- Ender Konukoglu
- Dennis W. Dickson
Citations in the corpus
- Inflammatory processes in Alzheimer's disease. (2007, positive): “Interestingly, LC loss correlates better with the clinical course of the disease and the severity of dementia than loss of the nucleus basalis of Meynert and perturbation of the cholinergic system (Zarow et al., 2003).”
- Missing pieces in the Parkinson's disease puzzle (2010, background): “Affected nondopamine neurons include monoaminergic cells in the locus coeruleu”
- The pathological process underlying Alzheimer’s disease in individuals under thirty (2011, background): “Unfortunately, however, it is also presently unknown what developmental phase the AD-associated intraneuronal lesions have to reach before physiologically measurable cell dysfunctions occur, which, in turn, once sufficiently large percentages of principal nerve cells in a given brain region have bec”