Vasopressin versus norepinephrine infusion in patients with septic shock.

By J. Russell, K. Walley, J. Singer, A. Gordon, Paul C. Hébert, D. Cooper, C. L. Holmes, S. Mehta, J. Granton, Michelle Storms and 3 more. New England Journal of Medicine, 2008

1,571 citations recorded by the source corpus.

Subfields: Critical Care and Intensive Care Medicine, Epidemiology, Surgery

View Paper: https://www.semanticscholar.org/paper/c7d49fda23c422c77b8d20c0efcdc89e2cef8bb6

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Citations in the corpus

Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: Consensus statements from an international task force by the American College of Critical Care Medicine (2008, background): “Although it has been suggested that clinical equipoise existed during enrollment into the CORTICUS study (107), many intensivists continue to use corticosteroids in the management of patients with septic shock (108, 109).”
CONSORT 2010 Explanation and Elaboration: updated guidelines for reporting parallel group randomised trials (2010, methodology): “’’[293] ExplanationdA protocol for the complete trial (rather than a protocol of a specific procedure within a trial) is important because it pre-specifies the methods of the randomised trial, such as the primary outcome (see item 6a).”
Fluid resuscitation in septic shock: A positive fluid balance and elevated central venous pressure are associated with increased mortality* (2011, background): “How should a clinician faced with a patient in vasopressor-dependent shock titrate fluid therapy? The VASST study provides an excellent opportunity to study the usual prescribing practices for intravenous fluids in patients with septic shock, because neither before nor after enrollment was there a m”
Drotrecogin alfa (activated) in adults with septic shock. (2012, methodology): “We used an adaptive design(22) that allowed us to increase the sample size to maintain adequate statistical power, since some trials involving patients with severe sepsis showed lower-thanexpected mortality.(19,23,24) To reduce the risk of assignment bias, we concealed study-group assignments before”
Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012 (2013, neutral): “population [166].”
Sepsis and septic shock. (2018, background): “96 In a UK multicentre RCT published in 2016, vasopressin did not decrease the number of kidney failure-free days 97 compared with norepinephrine.”
Effect of Early Vasopressin vs Norepinephrine on Kidney Failure in Patients With Septic Shock: The VANISH Randomized Clinical Trial. (2016, neutral): “Kidney failure–free days in other patients, median (IQR), de 5 (0-23) 12 (1-25) 9 (1-24) 13 (0-25) 14 (1-24) 13 (1-25) −4 (−11 to 5)d”
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before‐After Study (2017, methodology): “reported to vary between about 72 and 120 h.(37,54) In the VANISH (Vasopressin vs Noradrenaline as Initial Therapy in Septic Shock) trial, the median time to shock reversal was 45 h (interquartile range, 23-75 h).”
CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials. (2012, background): “Example d ‘‘Full details of the trial protocol can be found in the Supplementary Appendix, available with the full text of this article at www.nejm.org’’ [293].”