The pathogenesis of rheumatoid arthritis.

By A. Koch. American journal of orthopedics, 2007

2,985 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/c7295587172de6c19a94a76b06cc8a41d44a41e1

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1. J. Scher
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8. R. Longman

Citations in the corpus

• Autoantibodies, autoimmune risk alleles and clinical associations in rheumatoid arthritis cases and non-RA controls in the electronic medical records (2013, unknown): “The second explanation, not mutually exclusive from the genetic model, is that differential environmental and endogenous (immune dysregulation) exposures are associated with RA (40).”
• Rheumatoid arthritis: pathological mechanisms and modern pharmacologic therapies (2018, background): “apoptosis.(50) This results in cartilage degradation demonstrable as joint-space narrowing on radiography.”
• Update on the Pathomechanism, Diagnosis, and Treatment Options for Rheumatoid Arthritis (2020, background): “Therefore, besides activation of resident and infiltrating immune cells, joint inflammation in RA is also characterized by a specific tissue response in which local fibroblasts assume an aggressive pro-inflammatory phenotype characterized by matrix regulatory, osteoclast-generating, and invasive pro”
• Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis (2016, background): “Despite these treatment options, many RA patients fail to respond, instead persisting with poor health, shortened life span, and significant impairments in quality of life affecting work, leisure, and social functions (5, 6).”
• Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis (2013, background): “Despite recent advances towards understanding its pathogenesis (Mcinnes and Schett, 2011), the etiology of RA remains elusive.”
• The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY (2017, background): “Most chronic diseases, including ageing, have an immune-inflammatory component (10); auto-immunity is a serious problem (11,12), and the progress of infections depends on immune and inflammatory responses (13).”
• Immunopathogenesis of rheumatoid arthritis (2017, unknown): “Recent insights into the participation of sclerostin, DKK, ACPAs, and other osteoclast and osteoblast co-regulators suggest the intriguing possibility of promoting bone healing—this has not yet been possible on the basis of existing therapeutics (Diarra et al., 2007; McInnes and Schett, 2011).”
• Age and Age-Related Diseases: Role of Inflammation Triggers and Cytokines (2018, background): “This complex cytokine milieu attracts further immune cells, promotes abnormal angiogenesis and osteoclastogenesis, poorly formed leaky vasculature and leads to systemic effects (309).”
• NF-κB signaling in inflammation (2017, unknown): “74 A major inflammatory mediator of RA is NF-κ B, which has been demonstrated in studies using both animal models and human patients.”