A Common Variant on Chromosome 9p21 Affects the Risk of Myocardial Infarction

By A. Helgadóttir, G. Thorleifsson, A. Manolescu, S. Gretarsdottir, T. Blondal, Á. Jónasdóttir, Adalbjorg Jonasdottir, A. Sigurdsson, A. Baker, Arnar Pálsson and 25 more. Science, 2007

898 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/c6c5bbe025441bb878530bbd85db55cb110ef15a

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Citations in the corpus

Human genetic variation and its contribution to complex traits (2009, background): “Another example is the common SNP on chromosome 9p21 that is associated with three vascular phenotypes — myocardial infarctio”
Genome–wide association studies provide new insights into type 2 diabetes aetiology (2007, background): “Interestingly, recent GWAS have identified a separate set of SNPs that seem to represent the strongest common genetic risk factor for heart disease (myocardial infarction”
Mapping the Genetic Architecture of Gene Expression in Human Liver (2008, background): “now delivered a number of novel findings across a diversity of diseases, including age-related macular degeneration [1–3], heart disease [4,5], host control of HIV-1 [6], type I and II diabetes [7,8], and obesity [9].”
The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm (2008, background): “72" language="eng" relation="no"> Recently, two common sequence variants on 9p21, tagged by rs10757278-G and rs10811661-T, were reported to be associated with coronary artery disease (CAD”