Plasma medicine: an introductory review

By Michael G. Kong, Gmw Gerrit Kroesen, G. Morfill, T. Nosenko, Tetsuji Shimizu, V. J. Dijk, J. Zimmermann. 2009

1,492 citations recorded by the source corpus.

This introductory review on plasma health care is intended to provide the interested reader with a summary of the current status of this emerging field, its scope, and its broad interdisciplinary approach, ranging from plasma physics, chemistry and technology, to microbiology, biochemistry, biophysics, medicine and hygiene. Apart from the basic plasma processes and the restrictions and requirements set by international health standards, the review focuses on plasma interaction with prokaryotic cells (bacteria), eukaryotic cells (mammalian cells), cell membranes, DNA etc. In so doing, some of the unfamiliar terminology—an unavoidable by-product of interdisciplinary research—is covered and explained. Plasma health care may provide a fast and efficient new path for effective hospital (and other public buildings) hygiene—helping to prevent and contain diseases that are continuously gaining ground as resistance of pathogens to antibiotics grows. The delivery of medically active ‘substances’ at the molecular or ionic level is another exciting topic of research through effects on cell walls (permeabilization), cell excitation (paracrine action) and the introduction of reactive species into cell cytoplasm. Electric fields, charging of surfaces, current flows etc can also affect tissue in a controlled way. The field is young and hopes are high. It is fitting to cover the beginnings in New Journal of Physics, since it is the physics (and non-equilibrium chemistry) of room temperature atmospheric pressure plasmas that have made this development of plasma health care possible.

Subfields: Electrical and Electronic Engineering, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/c659b02ca40b7abaae8d9d7eb512c0dccfe7bd32

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Citations in the corpus

Cold plasma selectivity and the possibility of a paradigm shift in cancer therapy (2011, background): “The potential use in biomedical applications has driven the development of a variety of reliable and userfriendly plasma sources (Laroussi and Lu, 2005; Becker et al, 2006; Stoffels et al, 2006; Fridman et al, 2008; Kong et al, 2009; Morfill et al, 2009).”
Quantitative detection of plasma-generated radicals in liquids by electron paramagnetic resonance spectroscopy (2013, neutral): “pressure plasmas [4, 6–8].”
Low temperature atmospheric pressure plasma sources for microbial decontamination (2011, background): “But also emerging application areas like plasma healthcare can be approachable by the usage of non-LTE plasmas (Stoffels, 2007; Kong et al., 2009; Morfill, Kong and Zimmermann, 2009; Lloyd et al., 2010; Laroussi, 2009; Fridman et al., 2008).”
Physicochemical properties of bactericidal plasma-treated water (2016, background): “Many studies have investigated the potential applications of LTAPP; in particular, the field of plasma medicine has attracted intense interest [3–5] with regards to enhanced wound healing [3, 4, 6], cancer therapy [7, 8], inactivation of pathogenic amyloids [9, 10], disinfection of the human body or”
Reactive nitrogen species in plasma-activated water: generation, chemistry and application in agriculture (2020, neutral): “involve plasma interactions with cells [1, 2].”