Factors affecting the composition of the gut microbiota, and its modulation
By Nihal Hasan, Hongyi Yang. PeerJ, 2019
631 citations recorded by the source corpus.
Gut microbiota have important functions in the body, and imbalances in the composition and diversity of those microbiota can cause several diseases. The host fosters favorable microbiota by releasing specific factors, such as microRNAs, and nonspecific factors, such as antimicrobial peptides, mucus and immunoglobulin A that encourage the growth of specific types of bacteria and inhibit the growth of others. Diet, antibiotics, and age can change gut microbiota, and many studies have shown the relationship between disorders of the microbiota and several diseases and reported some ways to modulate that balance. In this review, we highlight how the host shapes its gut microbiota via specific and nonspecific factors, how environmental and nutritional factors affect it, and how to modulate it using prebiotics, probiotics, and fecal microbiota transplantation.
Subfields: Gastroenterology, Infectious Diseases, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/bca7cc8e2ed9ba78da09936100697387b4c54e03
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Gastroenterology
In Infectious Diseases
In Molecular Biology
Citations in the corpus
- Human gut microbiota/microbiome in health and diseases: a review (2020, background): “Among these factors are host genetics, diet, age (Odamaki et al. 2016), mode of birth (Nagpal et al. 2017) and antibiotics (Hasan and Yang 2019).”