Aquaporins in the kidney: from molecules to medicine.

By S. Nielsen, J. Frøkiaer, D. Marples, T. Kwon, P. Agre, M. Knepper. Physiological Reviews, 2002

1,233 citations recorded by the source corpus.

Subfields: Molecular Biology, Pulmonary and Respiratory Medicine

View Paper: https://www.semanticscholar.org/paper/c5a473efa8cc4d34db6ba3dc8087dcd3b6459a19

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In Molecular Biology

In Pulmonary and Respiratory Medicine

Citations in the corpus

Desalination by biomimetic aquaporin membranes: Review of status and prospects (2013, background): “Several recent reviews have nicely summarized many fascinating aspects of aquaporin protein structure and function [7–11].”
The human urinary proteome contains more than 1500 proteins, including a large proportion of membrane proteins (2006, background): “Furthermore, we identified three aquaporins, namely AQP1, AQP2 and AQP7, which are all aquaporins known to localize to the apical plasma membrane in the kidney, whereas we did not identify any aquaporins that are known to be expressed on the basolateral plasma membrane [43,44].”
Aquaporin Water Channels (2004, background): “Thus, AQP2 is very important in clinical medicine (reviewed by Nielsen et al., 2002).”
Biomimetic aquaporin membranes coming of age (2015, background): “This implies that most of the water and solutes are re-circulated and this transport is to a large extent mediated by a complex interplay between active and passive facilitators, where AQPs play a key role [7].”
Physiological roles of aquaporin-4 in brain. (2013, background): “Notably, with the identification of aquaporin-2 (AQP2), it soon became possible to describe in molecular terms how the kidney regulates urine production and thus helps maintain systemic fluid balance (128).”
From structure to disease: the evolving tale of aquaporin biology (2004, background): “Each kidney contains approximately one million nephrons, and each nephron segment has a well-defined water permeability that correlates with the presence or absence of different aquaporin”