Physiological roles of aquaporin-4 in brain.
By Erlend A. Nagelhus, Ole Petter Ottersen. Physiological Reviews, 2013
687 citations recorded by the source corpus.
Subfields: Molecular Biology, Pharmacology, Pulmonary and Respiratory Medicine
View Paper: https://www.semanticscholar.org/paper/be85c711db8001532b081359235fcd03c19944e6
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Citations in the corpus
- The blood–brain barrier: Structure, regulation and drug delivery (2023, background): “60,61 69 Some studies considered astrocytes can arise barrier behaviors in cerebral, other endothelial cells, and related epithelial, while other studies thought the BBB goes fi rst before the appearance of astrocytes.”
- Glymphatic MRI in idiopathic normal pressure hydrocephalus (2017, background): “Astrocytic end feet enclose all parenchymal brain vessels, and the water channel AQP4 occupies up to 40% of the end foot area, rendering a vast surface for water transport throughout the entire brain (Nagelhus and Ottersen, 2013).”
- Physiology of Astroglia. (2018, neutral): “Finally, genetic deletion of AQP4 significantly modifies various neuropathologies (1184).”
- Impairment of Glymphatic Pathway Function Promotes Tau Pathology after Traumatic Brain Injury (2014, background): “…initiation sites: the longer AQP4-M23 variant that is predominant in healthy brain and exhibits highly polarized perivascular localization (Nagelhus and Ottersen, 2013) and the shorter AQP4-M1 form that does not polarize (Furman et al., 2003; Crane et al., 2009), but facilitates astrocyte…”
- Impairment of paravascular clearance pathways in the aging brain (2014, background): “Perivascular AQP4 Polarization Is Impaired in the Aging Brain AQP4, an astroglial water channel, is localized in a highly polarized manner to endfoot processes surrounding the cerebral vasculature in addition to the glial limitans externa, which abuts the pia mater and bounds the subarachnoid CSF co”