Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice
By Vanessa K. Ridaura, Jeremiah J. Faith, Federico E. Rey, Jiye Cheng, A. Duncan, A. L. Kau, Nicholas W. Griffin, Vincent Lombard, B. Henrissat, R. James and 18 more. Science, 2013
3,172 citations recorded by the source corpus.
Subfields: Molecular Biology, Physiology
View Paper: https://www.semanticscholar.org/paper/c554c3579baee17a66beee195c8b7c9578d18163
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In Molecular Biology
- J. Cryan
- Rob Knight
- Ted G. Dinan
- S. Mazmanian
- G. Clarke
- Jeffrey I. Gordon
- Catherine A. Lozupone
- C. Stanton
In Physiology
- Rob Knight
- J. Cryan
- Ted G. Dinan
- G. Clarke
- Catherine A. Lozupone
- L. Ursell
- Jeffrey I. Gordon
- Jeroen Raes
Citations in the corpus
- Correlation detection strategies in microbial data sets vary widely in sensitivity and precision (2016, positive): “…in numerous human health conditions including obesity and metabolic syndrome (Ley et al., 2005; Turnbaugh et al., 2009; Vrieze et al., 2012; Ridaura et al., 2013), cardiovascular disease (Wang et al., 2011), Clostridium difficile colitis (Gough et al., 2011), inflammatory bowel diseases…”
- Identifying Keystone Species in the Human Gut Microbiome from Metagenomic Timeseries Using Sparse Linear Regression (2014, positive): “Ridaura et al [4] demonstrated that transplants of gut microbial consortia are sufficient to induce obesity in previously lean mice or to promote weight loss in previously obese mice, suggesting an”
- Meta-analyses of human gut microbes associated with obesity and IBD (2014, neutral): “In contrast, the differences between obese and lean individuals, even though these differences can be transmitted to recipient gnotobiotic mice [32], are much less consistent.”
- Conducting a Microbiome Study (2014, neutral): “Separately maintained mice can then be cohoused to demonstrate the spread of a microbiota between adults (Lawley et al., 2012; Ridaura et al., 2013).”
- Gut microbiota-derived metabolites as central regulators in metabolic disorders (2020, positive): “15 The effect of the gut microbiota seems to occur even before birth, as the maternal gut microbiota, through short-chain fatty acid (SCFAs), triggers embryonic GPR41 and GPR43 and influences prenatal development of neural, enteroendocrine and pancreatic systems of the offspring to maintain…”
- Impact of the gut microbiota on inflammation, obesity, and metabolic disease (2016, positive): “SCFAs repress NF-κB and affect the production of proinflammatory markers, such as IL-2 and IL-10, in leukocytes [82].”