Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion

By D. Iliopoulos, Heather A. Hirsch, Guannan Wang, Kevin Struhl. Proceedings of the National Academy of Sciences of the United States of America, 2011

638 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/c4cd77f1b8c316b21e3427775243884052dc2b65

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Herbert Levine
2. José N. Onuchic
3. You Han Bae
4. Kinam Park
5. P. Dirks
6. Martin Weigt

In Oncology

1. You Han Bae
2. Kinam Park
3. P. Dirks

Citations in the corpus

• Implications of the Hybrid Epithelial/Mesenchymal Phenotype in Metastasis (2015, background): “Cell–cell communication among cancer cells and/or between cancer cells and stromal cells (fibroblasts, immune cells, endothelial cells, etc.) can have a significant influence on phenotypic plasticity (EMT/MET), CSC self-renewal, and a dynamic equilibrium between CSCs and non-CSCs ( 125, 128).”
• Targeted drug delivery to tumors: Myths, reality and possibility (2011, positive): “At any one time in a tumor there can be different subpopulations of several stages of transition between these different cell phenotypes in a type of dynamic equilibrium [87].”
• Cancer stem cells: an evolving concept (2012, background): “The possibility that CSCs can undergo reversible fluctuations in their stem cell status has also been suggeste”