An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder.

By M. Jordan, David A Hildeman, J. Kappler, P. Marrack. Blood, 2004

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Confirmed efficacy of etoposide and dexamethasone in HLH treatment: long-term results of the cooperative HLH-2004 study. (2017, neutral): “5-y pSu (95% CI) 61 (56-67) 59 (52-67) 64 (57-71) 62 (56-68) 61 (53-70) 56 (50-63)”
COVID-19: Transmission, prevention, and potential therapeutic opportunities (2020, neutral): “Rituximab, Etoposide, and Lenumab are Mabs used to reduce CD8+ T cells, decrease the release of interferon-gamma, and to treat CRS and hemophagocytic lymphohistiocytosis (FHLH) [124,125].”
Functions of natural killer cells (2008, background): “The role of microbial infection in the onset of inherited HLH and reactive HLH is supported by experimental viral infection in mutant mic”
Familial and acquired hemophagocytic lymphohistiocytosis (2006, background): “The selective role of INF-γ, secreted by virus-activated cytotoxic cells and NK effectors, in the manifestation of HLH was demonstrated in a perforin knock-out mouse model [62].”