Human telomere biology: A contributory and interactive factor in aging, disease risks, and protection

By Elizabeth H Blackburn, E. Epel, Jue Lin. Science, 2015

1,402 citations recorded by the source corpus.

Subfields: Physiology

View Paper: https://www.semanticscholar.org/paper/c4160b1f5c1bb4f4a833b64fa29123353b9a725d

How researchers see this paper

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In Physiology

1. N. Pedersen
2. Juulia Jylhävä
3. Sara Hägg

Citations in the corpus

• Aging and aging-related diseases: from molecular mechanisms to interventions and treatments (2022, background): “Telomerase activity is highest in human embryonic tissues and decreases progressively with age.(60) In the classic view, telomerase protects certain frequently dividing cells in normal tissues, such as embryonic cells, sperm cells, adult stem cells, and immune cells, but it is inactive in other cell”
• Biological Age Predictors (2017, background): “Telomeres are repetitive DNA sequences capping chromosomes, which shorten every time cells divide; thus, telomere length is a popular marker of biological aging (Blackburn et al., 2006).”
• Benefits of Metformin in Attenuating the Hallmarks of Aging (2020, neutral): “undergo progressive attrition with cell proliferation (Blackburn et al. 2015).”