Comprehensive human genome amplification using multiple displacement amplification

By F. Dean, S. Hosono, Linhua Fang, Xiaohong Wu, A. Faruqi, P. Bray-Ward, Zhenyu Sun, Q. Zong, Yuefen Du, Jing Du and 5 more. Proceedings of the National Academy of Sciences of the United States of America, 2002

1,491 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/c2a3efb55417670320a85f752bc8e7fe77a6b36a

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In Genetics

1. Peter W. Laird
2. S. Primrose
3. J. Gregory Caporaso
4. Melanie Ehrlich
5. Ruth E. Ley
6. Dominic Grün
7. Rob Knight
8. R. Twyman

In Molecular Biology

1. Rob Knight
2. J. Gregory Caporaso
3. Ruth E. Ley
4. William Walters
5. Peter W. Laird
6. Omry Koren
7. Gaetano T. Montelione
8. Julia Goodrich

In Plant Science

1. J. Gregory Caporaso
2. Rob Knight
3. Alexander van Oudenaarden

Citations in the corpus

• CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes (2015, methodology): “All GFPpositive embryos were then collected for whole-genome amplification by multiplex displacement amplification (Dean et al., 2002; Hosono et al., 2003), followed by PCR amplification of the G1 gRNA target region and sequencing.”
• dPCR: A Technology Review (2018, background): “A wide variety of isothermal nucleic acid amplification technologies have been developed such as rolling circle amplification (RCA) [111], nucleic-acid sequence-based amplification (NASBA) [112], loop-mediated amplification (LAMP) [113], multiple displacement amplification (MDA) [114], helicase-depe”
• Principles of Gene Manipulation and Genomics (2006, methodology): “An alternative method of WGA that does not involve PCR has been developed and is called multiple displacement amplification (MDA) (Dean et al. 2002; Hosono et al. 2003).”
• Advanced sequencing technologies: methods and goals (2004, neutral): “This feature is relevant to all technologies,and we should take note that methods for amplifying large DNA molecules by MULTIPLE-DISPLACEMENT AMPLIFICATION or WHOLE-GENOME AMPLIFICATION are improving rapidly 52,53 .”
• Conducting a Microbiome Study (2014, methodology): “The whole-genome amplification methods MDA (multiple displacement amplification; Dean et al., 2002) and MALBAC (multiple annealing and looping-based amplification cycles; Zong et al., 2012) are generally preferred, as they are best able to maintain the diversity of DNAmolecules present in the…”
• Design and Analysis of Single-Cell Sequencing Experiments. (2015, methodology): “MDA utilizes isothermal amplification by a DNA polymerase with strand displacement activity, typically f29, initiated by random priming of denaturedDNA (Dean et al., 2002).”