Principles of Gene Manipulation and Genomics

By S. Primrose, R. Twyman. 2006

93 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/f7eb2aaaf3424fa70483abe07fb977f0bcd0e51e

Citations in the corpus

• Widespread shortening of 3′UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells (2009, unknown): “The overall repressive character of 3 0 UTRs could help explain why nearly all successful transgenic mouse models of tumorigenesis overexpress oncogenes missing large segments of their annotated 3 0 UTRs (Ruther et al., 1987; Fedele et al., 2002; Primrose and Twyman, 2006).”