An inhibitor of oxidative phosphorylation exploits cancer vulnerability
By J. Molina, Yuting Sun, Marina Protopopova, S. Gera, Madhavi Bandi, C. Bristow, Timothy J. McAfoos, Pietro Morlacchi, J. Ackroyd, Ahmed-Noor A. Agip and 56 more. Nature Medicine, 2018
808 citations recorded by the source corpus.
Subfields: Cancer Research, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/c26bbdc13b70d246e89b0e096360ed0420deed23
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In Cancer Research
In Molecular Biology
Citations in the corpus
- Metabolic reprogramming and cancer progression (2020, background): “Recently described OXPHOS inhibitors display enhanced toxicity against cultured cancer cells compared with either nontransformed cells or other cancer cells with metabolic properties that allow them to compensate forOXPHOS impairment (116, 117).”