Androgens decrease plasma adiponectin, an insulin-sensitizing adipocyte-derived protein.

By H. Nishizawa, I. Shimomura, K. Kishida, N. Maeda, H. Kuriyama, H. Nagaretani, M. Matsuda, H. Kondo, N. Furuyama, S. Kihara and 4 more. Diabetes, 2002

869 citations recorded by the source corpus.

Subfields: Endocrine and Autonomic Systems, Epidemiology, Physiology

View Paper: https://www.semanticscholar.org/paper/c21a9328fa68b8d94bc2756526ad24e3283c3f15

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Endocrine and Autonomic Systems

1. P. Havel
2. Sushil Kumar Jain
3. A. Achari

In Epidemiology

1. J. Díez
2. S. Fried
3. P. Iglesias
4. Sushil Kumar Jain
5. A. Achari

In Physiology

1. P. Havel
2. S. Fried
3. Sushil Kumar Jain
4. A. Achari

Citations in the corpus

• Sex differences in human adipose tissues – the biology of pear shape (2012, background): “Higher circulating adiponectin concentrations are also seen in women despite their higher adiposity, which is associated in both sexes with lower adiponectin levels [151-153].”
• Systemic inflammation in nonalcoholic fatty liver disease is characterized by elevated levels of CCL2. (2006, background): “Sex differences in plasma levels of adiponection are normally present [39], but if our findings reflect that the protective role of adiponectin in NAFLD is gender specific or whether it is due to low sample size will have to be further elucidated.”
• The role of the novel adipocyte-derived hormone adiponectin in human disease. (2003, background): “Treatment with testosterone in both sham-operated and castrated mice was accompanied by a reduction in plasma adiponectin, and, in 3T3-L1 adipocytes, testosterone also reduced adiponectin secretion, thus indicating that androgen-induced hypoadiponectinemia might be related to the high risks of insul”
• Adiponectin: more than just another fat cell hormone? (2003, background): “Decreased levels are found in men compared with women (12), and this may be androgen induced (33).”
• Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex (2003, background): “Furthermore, it was recently reported that androgens decrease plasma adiponectin concentrations in vivo as well as adiponectin secretion from 3T3-L1 adipocytes in vitro [55].”
• The emergence of the metabolic syndrome with menopause. (2003, background): “However, the only study evaluating adiponectin in menopause revealed no difference in pre- and postmenopausal women (35).”
• Adiponectin: action, regulation and association to insulin sensitivity (2005, neutral): “an inhibitory effect on adiponectin (25).”