IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex.

By S. Kotenko, G. Gallagher, V. Baurin, A. Lewis-Antes, Meiling Shen, Nital K. Shah, J. Langer, F. Sheikh, H. Dickensheets, R. Donnelly. Nature Immunology, 2003

1,067 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/c219f268ffa70d0ea7e63b92e6385144ae1e73fe

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Citations in the corpus

• The Airway Epithelium: Soldier in the Fight against Respiratory Viruses (2011, background): “These IFNs use a unique receptor complex composed of the IL-10 receptor beta (IL-10R ) chain and the IFN- R1 chain (50, 149, 261).”
• Shared and Distinct Functions of Type I and Type III Interferons (2019, unknown): “IFN gene families have evolved through gene duplication and divergence such that the complement of IFN genes varies among vertebrate species (Krause and Pestka, 2015).”
• Interferon signalling network in innate defence (2006, background): “Newly identified IFN members, IFN-λs or IL-28/29, have been identified by two different research groups (Kotenko et al., 2003; Sheppard et al., 2003; Vilcek, 2003) (Table 1).”
• IFN-Lambda (IFN-λ) Is Expressed in a Tissue-Dependent Fashion and Primarily Acts on Epithelial Cells In Vivo (2008, background): “Type III IFN (also called IFN-l or IL-28/29) is structurally and genetically close to the members of the IL-10 family of cytokines but displays type I IFN-like activity [14,15].”