Healed Plaque Ruptures and Sudden Coronary Death: Evidence That Subclinical Rupture Has a Role in Plaque Progression

By A. Burke, F. Kolodgie, A. Farb, D. Weber, G. Malcom, J. Smialek, Renu Virmani. Circulation, 2001

962 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine, Radiology, Nuclear Medicine and Imaging, Surgery

View Paper: https://www.semanticscholar.org/paper/c1a9c317070710f8518abbe0a5ae23322b76328d

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cardiology and Cardiovascular Medicine

1. Peter Libby
2. G. Hansson
3. S. Grundy
4. P. Ridker
5. J. Willerson
6. G. Assmann
7. S. Jackson
8. Douglas P. Zipes

In Radiology, Nuclear Medicine and Imaging

1. Erling Falk
2. J. Bentzon
3. Renu Virmani
4. Peter Libby
5. William Insull

In Surgery

1. Peter Libby
2. G. Hansson
3. Erling Falk
4. P. Ridker
5. Renu Virmani
6. J. Bentzon
7. S. Grundy
8. A. Finn

Citations in the corpus

• Mechanisms of plaque formation and rupture. (2014, background): “present, and the number of healed ruptures correlates with the severity of stenosis.(105) Other plaques may have a multilayered”
• The Vascular Endothelium and Human Diseases (2013, background): “Furthermore, thrombus reorganization following subacute rupture has been proposed as a mechanism for lesion progression (37-39).”
• From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II. (2003, methodology): “Thrombotic complications that arise from rupture or fissure (small rupture) of a vulnerable plaque may be clinically silent, yet contribute to the natural history of plaque progression and ultimately luminal stenosis [31, 32].”
• Update on acute coronary syndromes: the pathologists' view. (2013, background): “Furthermore, clinically silent plaque rupture is not a rare phenomenon,(48,49) and plaque rupture with mural thrombosis appears to be a common cause of episodic but asymptomatic progression to severe stenosis.(50,51) These pathoanatomical findings explain classical clinical observations,”
• Arterial thrombosis—insidious, unpredictable and deadly (2011, background): “These thrombi, which are often asymptomatic, have an important role in promoting the rapid progression of the underlying atherosclerotic lesion”
• From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I. (2003, background): “Therefore, an active fibrinolytic system may be able to prevent luminal thrombosis in some cases of plaque disruption [119, 120].”