Characteristics of two distinct clinical phenotypes in pathologically proven progressive supranuclear palsy: Richardson's syndrome and PSP-parkinsonism.

By David R. Williams, Rohan de Silva, D. Paviour, A. Pittman, H. Watt, L. Kilford, J. Holton, T. Révész, Andrew Lees. Brain : a journal of neurology, 2005

730 citations recorded by the source corpus.

Subfields: Neurology, Physiology

View Paper: https://www.semanticscholar.org/paper/57fa7df8ba4b860e7465433914d2e21988c3c739

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Neurology

1. Kailash Bhatia
2. Dennis W. Dickson
3. Ronald C. Petersen
4. Clifford R. Jack Jr.
5. Michael D. Geschwind
6. Michael G. Erkkinen
7. Mee‐Ohk Kim

In Physiology

1. Clifford R. Jack Jr.
2. Ronald C. Petersen
3. Brad Boeve
4. David S. Knopman
5. Joseph E. Parisi
6. Dennis W. Dickson
7. Michael D. Geschwind
8. Michael G. Erkkinen

Citations in the corpus

• Parkinson's disease and parkinsonism: neuropathology. (2012, background): “Heterogeneity in the distribution of tau pathology in PSP is increasingly recognized (Williams et al. 2005; Dickson et al. 2010), but a staging scheme remains to be defined.”
• Clinicopathological and imaging correlates of progressive aphasia and apraxia of speech. (2006, background): “…the basis of presenting features: PSP-parkinsonism for those with a Parkinson's disease-like phenotype with partial L-dopa response, and Richardson's syndrome for those with a typical PSP presentation with early falls, vertical supranuclear gaze palsy and Ldopa resistance (Williams et al., 2005).”
• Clinical Neurology and Epidemiology of the Major Neurodegenerative Diseases. (2018, background): “…with a number of additional clinical phenotypes other than Steele–Richardson–Olszewski syndrome, including other PSP variants (PSP-parkinsonism [Williams et al. 2005], PSP-pure akinesia [Facheris et al. 2008], and PSP-primary progressive freezing gait [Compta et al. 2007], Advanced Online…”
• Clinical diagnosis of progressive supranuclear palsy: The movement disorder society criteria (2017, background): “four domains as most representative of characteristic disease manifestations.(9,10) Within each domain, we”
• A clinical rating scale for progressive supranuclear palsy. (2007, result): “We created the ‘gait ratio’ variable as an attempt to confirm in our subject group the recent observation (Williams et al., 2005) that patients with autopsy-confirmed PSP tend to fall into two clinical syndromes.”