Cyclooxygenase inhibitors--current status and future prospects.

By G. Dannhardt, W. Kiefer. European journal of medicinal chemistry, 2001

644 citations recorded by the source corpus.

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Algal Polysaccharides, Novel Applications and Outlook (2012, methodology): “and (2) The carrageenan-induced rat paw edema assay (Dannhardt and Kiefer 2001).”
Bioactive compounds in seaweed: functional food applications and legislation (2011, methodology): “Two test systems are used widely for the evaluation of non-steroidal antiinflammatory drugs and cyclooxygenase activity: (1) the carrageenan air pouch model and (2) the carrageenaninduced rat paw oedema assay (Dannhardt and Kiefer 2001).”
Medicinal and pharmaceutical uses of seaweed natural products: A review (2004, methodology): “The carrageenan-induced rat paw edema assay and carrageenan air pouch models are widely used as test systems for the evaluation of non-steroidal antiinflammatory drugs and cyclooxygenase activity (Wallace, 1999; Dannhardt & Kiefer, 2001).”
Cyclooxygenase Isozymes: The Biology of Prostaglandin Synthesis and Inhibition (2004, background): “Evidence that NSAIDs reduce cancer incidence and evoke tumor regression in the GI tract has been extensively reviewed elsewhere (Dannhardt and Kiefer, 2001; Dempke et al., 2001), as has overexpression of COX-2 in epithelial cancers in humans (Howe et al., 2001; Kalgutkar and Zhao, 2001; Tsuji et…”