Combination Therapy Versus Monotherapy in Reducing Blood Pressure: Meta-analysis on 11,000 Participants from 42 Trials

By W. J. Elliott. 2010

723 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine, Endocrinology, Diabetes and Metabolism, Pharmacology

View Paper: https://www.semanticscholar.org/paper/c04b5c1ac4529ef677d072e3de7e617a7fe32406

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cardiology and Cardiovascular Medicine

1. I. Graham
2. Jose Luis Zamorano
3. George Davey Smith
4. T. Ivanova

In Endocrinology, Diabetes and Metabolism

1. I. Graham
2. L. Rydén

In Pharmacology

1. I. Graham

Citations in the corpus

• Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies (2009, background): “A randomised trial carried out to assess the effects of blood pressure lowering drugs on sexual function confirmed the recognised effects of thiazides but showed that other classes of blood pressure lowering drug (including β blockers) did not differ from placebo.”
• European Guidelines on Cardiovascular Disease Prevention in Clinical Practice (Version 2012) (2012, positive): “The extra BP reduction from combining drugs from two different classes is approximately five times greater than doubling the dose of one drug.(428) The combination of two drugs may also offer advantages for treatment initiation, particularly in patients at high risk in whom early BP control may be d”