Mast cell-deficient W-sash c-kit mutant Kit W-sh/W-sh mice as a model for investigating mast cell biology in vivo.

By M. Grimbaldeston, C. Chen, A. Piliponsky, M. Tsai, S. Tam, S. Galli. American Journal of Pathology, 2005

622 citations recorded by the source corpus.

Subfields: Cell Biology, Immunology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/c01653e764bb92febeed3f493be35baa6066f038

Citations in the corpus

• Deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice (2009, neutral): “Earlier studies revealed normal numbers and activities of monocytes or macrophages and neutrophils in WT and Kit W-sh/W-sh mic”
• Innate immunity in the central nervous system. (2012, neutral): “The c-kit–mutant mice have additional hematologic and developmental abnormalities, and it is therefore essential to use mast cell reconstitution to confirm that the observed phenotypic differences between wild type and Kit mutant mice are mast cell dependent (148, 149).”