Longitudinal Magnetic Resonance Imaging Studies of Older Adults: A Shrinking Brain

By Susan M. Resnick, Dzung L. Pham, Michael A. Kraut, A. Zonderman, Christos Davatzikos. Journal of Neuroscience, 2003

1,405 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Psychiatry and Mental health, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/bfeb3d16a48b60458c19697495bc7dd17277f1e3

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Citations in the corpus

Homocysteine-Lowering by B Vitamins Slows the Rate of Accelerated Brain Atrophy in Mild Cognitive Impairment: A Randomized Controlled Trial (2010, neutral): “The atrophy occurs even in cognitively healthy subjects [1] but is much accelerated in patients suffering from Alzheimer’s disease [2,3,4,5].”
Spatial patterns of brain atrophy in MCI patients, identified via high-dimensional pattern classification, predict subsequent cognitive decline (2008, methodology): “, 2001) and applied to a variety of studies (Resnick et al., 2000; Resnick et al., 2001; Kim et al., 2003; Resnick et al., 2003; Resnick et al., 2004; Beresford et al., 2006; Beresford et al., 2006; Gur et al., 2006; Stewart et al., 2006; Driscoll et al., 2007).”
Regional brain changes in aging healthy adults: general trends, individual differences and modifiers. (2005, background): “Three exceptions are longitudinal studies revealing significant shrinkage of prefrontal regions with smaller but significant declines of other regions (Pfefferbaum et al., 1998; Resnick et al., 2003; Scahill et al., 2003).”
Differential vulnerability of anterior white matter in nondemented aging with minimal acceleration in dementia of the Alzheimer type: evidence from diffusion tensor imaging. (2004, background): “Recent longitudinal data also indicate greater changes in frontal (and parietal) regions ( Resnick et al., 2003 ).”
Insights into the ageing mind: a view from cognitive neuroscience (2004, background): “In post-mortem and in vivo studies, the brains of older adults tend to have lower volumes of grey matter than do the brains of younger adult”
Longitudinal Changes in Cortical Thickness Associated with Normal Aging (2010, background): “In older individuals, longitudinal decreases in gray and white matter volumes are widespread, and these declines are observed even in very healthy subjects during normal aging (Resnick et al., 2003).”
Baseline and longitudinal patterns of brain atrophy in MCI patients, and their use in prediction of short-term conversion to AD: Results from ADNI (2008, positive): “…has been extensively validated (Goldszal et al.,1998; Davatzikos et al., 2001) and applied to a variety of studies (Resnick et al., 2000; Resnick et al., 2001; Kim et al., 2003; Resnick et al., 2003, 2004; Beresford et al., 2006a,b; Gur et al., 2006; Driscoll et al., 2007; Stewart et al., 2006).”
Learning Implicit Brain MRI Manifolds with Deep Learning (2018, background): “9 years old) as part of the Baltimore Longitudinal Study of Aging (BLSA) study, which is a study of aging operated by the National Institute of Aging [15].”
Structural and functional biomarkers of prodromal Alzheimer's disease: A high-dimensional pattern classification study (2008, methodology): “The RAVENS approach has been extensively validated (Davatzikos et al., 2001; Goldszal et al., 1998) and applied to a variety of studies (Beresford et al., 2006a,b; Driscoll et al., 2007; Gur et al., 2006; Kim et al., 2003; Resnick et al., 2001, 2004, 2000, 2003; Stewart et al., 2006).”
One year brain atrophy evident in healthy aging (2009, background): “Atrophy rates in other parts of the brain are seldom studied, with a few important exceptions (Pfefferbaum et al., 1998; Resnick et al., 2003; Raz et al., 2005; Driscoll et al., 2009).”
Estimating the age of healthy subjects from T1-weighted MRI scans using kernel methods: Exploring the influence of various parameters (2010, neutral): “, 2009) as well as longitudinal data comparison (Resnick et al., 2003).”
Life-span changes of the human brain white matter: diffusion tensor imaging (DTI) and volumetry. (2010, background): “…with protracted growth extending into the fifth or sixth decade with subsequent accelerating decrease (Courchesne et al. 2000; Jernigan et al. 2001; Resnick et al. 2003; Allen et al. 2005; Fotenos et al. 2005; Raz et al. 2005; Ikram et al. 2008; Salat, Greve, et al. 2009; Walhovd et al.…”
Trajectories of brain aging in middle-aged and older adults: Regional and individual differences (2010, positive): “Moreover, the regional rates of age-related declines may depend on common age-related vascular risk factors (Resnick et al., 2003; Raz et al., 2007, 2008) and genetic variants such as ε4 allele of the apolipoprotein E (ApoE) gene (Moffat et al.”
A unified approach for morphometric and functional data analysis in young, old, and demented adults using automated atlas-based head size normalization: reliability and validation against manual measurement of total intracranial volume (2004, positive): “Second, atlas-based normalization provides a direct means of head normalization for morphometric analysis: measurements can be made directly on the atlas-transformed images (see Goldszal et al., 1998, for an interesting, related approach; see applications of their procedure in Resnick et al., 2000,”
What is normal in normal aging? Effects of Aging, Amyloid and Alzheimer’s Disease on the Cerebral Cortex and the Hippocampus (2014, background): “First, Resnick and colleagues followed 92 healthy elderly from the Baltimore Longitudinal Study of Aging for four years, and found significant reductions in brain volume in all cortical lobes (Resnick et al., 2003).”
Accelerated Brain Gray Matter Loss in Fibromyalgia Patients: Premature Aging of the Brain? (2007, result): “The age-related decrease was even greater than that observed by Resnick et al. (2003) in a much older group of healthy adults (59 – 85 years), with the fibromyalgia patients in our study showing a decrease of 3.7 cm 3/year and the older healthy subjects showing a decrease of 2.4 cm 3/year.”