Surface functionalization of nanoparticles for nanomedicine

By R. Mout, Daniel F. Moyano, S. Rana, Vincent Rotello. Chemical Society Reviews, 2012

699 citations recorded by the source corpus.

Control of interactions between nanoparticles and biosystems is essential for the effective utilization of these materials in biomedicine. A wide variety of nanoparticle surface structures have been developed for imaging, sensing, and delivery applications. In this research Highlight, we will emphasize advances in tailoring nanoparticle interfaces for implementation in nanomedicine.

Subfields: Biomaterials, Electronic, Optical and Magnetic Materials, Materials Chemistry

View Paper: https://www.semanticscholar.org/paper/bf32c0142a013ee0b3ec6a7317b4dfa23292b065

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In Biomaterials

In Electronic, Optical and Magnetic Materials

In Materials Chemistry

Citations in the corpus

Nanotechnology for increased micronutrient bioavailability (2014, background): “The authors refer to Oehlke et al. (2014) and McClements and Xiao (2012) for reviews related to this topic.”
Dynamic light scattering for gold nanorod size characterization and study of nanorod–protein interactions (2012, background): “The potential interactions between nanoparticle materials and various biomolecules, particularly proteins, are a major research topic [14, 15].”
Advanced nanomaterials in oil and gas industry: Design, application and challenges (2017, background): “and/or organic solutions [7,208,209], to enable self-organization [210–212] and to obtain specific functionalities such as for catalytic activities [213,214], biocompatibility [215,216] or for specific binding capabilities as in biomedical applications [217,218].”
High drug-loading nanomedicines: progress, current status, and prospects (2017, positive): “One way to bypass this problem is surface functionalization by introducing PEG and other coatings to reduce immunorecognition.(71,72) The other is harnessing this natural effect and using it in immunobased treatments.”
Insight into nanoparticle cellular uptake and intracellular targeting (2014, positive): “With some nanomedicines alreadymaking their way into the clinic, liposomes, polymeric nanoparticles, dendrimers, and gold nanoparticles have demonstrated remarkable potential as carrier systems [5–8].”