Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia

By R. Romee, M. Rosario, M. Berrien-Elliott, Julia A Wagner, Brea A. Jewell, Timothy Schappe, Jeffrey W. Leong, Sara Abdel-Latif, Stephanie E. Schneider, Sarah Willey and 8 more. Science Translational Medicine, 2016

823 citations recorded by the source corpus.

Subfields: Hematology, Immunology

View Paper: https://www.semanticscholar.org/paper/becb778b88e8dd67368372cba44c7e76c7465e65

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In Immunology

1. G. Lal
2. S. Paul

Citations in the corpus

• The Molecular Mechanism of Natural Killer Cells Function and Its Importance in Cancer Immunotherapy (2017, background): “Furthermore, its therapeutic use resulted in complete remission of nine AML patients in phase I clinical trial (127).”
• CAR-NK cells: A promising cellular immunotherapy for cancer (2020, background): “Despite the safety and promising clinical efficacy of unmodified allogenic NK cells particularly for AML [92] and the potential to Ta bl e 2 CA R- N K ce ll cl in ic al tr ia ls .”
• Natural killer cells in cancer biology and therapy (2020, background): “Memory-like NK cells supplemented with IL-12, IL-15 and IL-18 also show enhanced responses against acute myeloid leukemia both in vitro and in vivo [107], and are currently assessed in a first-in-human clinical trial.”