GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current

By Jane E. Lauckner, Jill B Jensen, H. Chen, Hui-Chen Lu, Bertil Hille, K. Mackie. Proceedings of the National Academy of Sciences of the United States of America, 2008

708 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Pharmacology

View Paper: https://www.semanticscholar.org/paper/bdad2b9996dc5527f5d6dacf2b5e394ffad6e8c8

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. R. Pertwee
2. V. Di Marzo
3. R. Ross
4. George Kunos
5. K. Mackie
6. R. Mechoulam
7. Allyn C. Howlett
8. Stephen P. H. Alexander

In Pharmacology

1. R. Pertwee
2. V. Di Marzo
3. George Kunos
4. R. Ross
5. R. Mechoulam
6. K. Mackie
7. Allyn C. Howlett
8. P. Greasley

Citations in the corpus

• Antioxidative and Anti-Inflammatory Properties of Cannabidiol (2019, background): “Activation of GPR55 increases the intracellular level of calcium ions [94].”
• Alcoholism: a systems approach from molecular physiology to addictive behavior. (2009, background): “The endocannabinoid system includes CB1, CB2, and the orphan receptor GPR55 as a new CB receptor (261), endocannabinoids, e.”
• CB2: a cannabinoid receptor with an identity crisis (2010, background): “, 2000), but has since been shown to also be an agonist at GPR55 (Ryberg et al., 2007; Lauckner et al., 2008).”
• International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2 (2010, methodology): “GPR55 has also been shown by other methods to use G q , G 12 , or G 13 for signal transduction, which results in downstream activation of RhoA and PLC (Lauckner et al., 2008; Henstridge et al., 2009; Kapur et al., 2009).”