PDF cells are a GABA-responsive wake-promoting component of the Drosophila sleep circuit.
By Katherine M. Parisky, José L. Agosto, S. Pulver, Yuhua Shang, E. Kuklin, James J. L. Hodge, KyeongJin Kang, Xu Liu, P. Garrity, M. Rosbash and 1 more. 2008
409 citations recorded by the source corpus.
Subfields: Cellular and Molecular Neuroscience, Endocrine and Autonomic Systems, Genetics
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In Cellular and Molecular Neuroscience
Citations in the corpus
- Mushroom body output neurons encode valence and guide memory-based action selection in Drosophila (2014, neutral): “…defined as sustained periods of inactivity (5 min or more) that coincide with increased sensory thresholds, altered brain activity and stereotyped body posture (Hendricks et al., 2000; Shaw et al., 2000; Hendricks and Sehgal, 2004; Ganguly-Fitzgerald et al., 2006; Parisky et al., 2008; Figure 7.”
- Short neuropeptide F is a sleep-promoting inhibitory modulator (2013, positive): “The main neurochemical previously implicated in fly arousal is DA (Andretic and Shaw, 2005), and l-LNvs play a prominent role in the arousal circuitry (Lebestky et al., 2009; Parisky et al., 2008; Shang et al., 2008; Sheeba et al., 2008).”
- Genetic manipulation of genes and cells in the nervous system of the fruit fly (2011, neutral): “…of Neuronal Activity UAS-dnATPase (D369N) Dominant-negative Na+/ K+ ATPase Blocks membrane repolarization pump Sun et al. 2001; Parisky et al., 2008 UAS-NaChBac Bacterial sodium channel Increases sodium conductance Nitabach et al., 2006; Sheeba et al., 2008 UAS-TrpVR1…”
- Analysis of functional neuronal connectivity in the Drosophila brain. (2012, neutral): “…also suggests that the excitation of the l-LN v s, neurons important for the control of arousal, sleep, and the integration of circadian light input (Parisky et al. 2008; Shang et al. 2008; Sheeba et al. 2008), does not result in large acute Ca 2ϩ increases in the critical s-LN v pacemaker neurons.”