Innate immunity in plants: An arms race between pattern recognition receptors in plants and effectors in microbial pathogens

By T. Boller, S. He. Science, 2009

1,018 citations recorded by the source corpus.

For many years, research on a suite of plant defense responses that begin when plants are exposed to general microbial elicitors was underappreciated, for a good reason: There has been no critical experimental demonstration of their importance in mediating plant resistance during pathogen infection. Today, these microbial elicitors are named pathogen- or microbe-associated molecular patterns (PAMPs or MAMPs) and the plant responses are known as PAMP-triggered immunity (PTI). Recent studies provide an elegant explanation for the difficulty of demonstrating the role of PTI in plant disease resistance. It turns out that the important contribution of PTI to disease resistance is masked by pathogen virulence effectors that have evolved to suppress it.

Subfields: Plant Science

View Paper: https://www.semanticscholar.org/paper/bd64f461bf8bdfa837d8e2c25a3e6b21961e3893

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In Plant Science

Citations in the corpus

A CRISPR/Cas9 Toolbox for Multiplexed Plant Genome Editing and Transcriptional Regulation1[OPEN] (2015, background): “FLS2 and BAK1 are important immune receptor or co-receptor genes in 246 Arabidopsis (Boller and Felix, 2009; Boller and He, 2009).”
A receptor-like cytoplasmic kinase, BIK1, associates with a flagellin receptor complex to initiate plant innate immunity (2009, background): “Discussion Plants and animals respond to an array of MAMPs from both pathogenic and nonpathogenic microbes and activate convergent immune signaling (1, 4).”
Signaling in Plant-Microbe Interactions (2013, background): “These T3Es promote pathogenicity by modulating host defense signaling and suppressing PTI (Alfano and Collmer 2004; Jones and Dangl 2006; Boller and He 2009).”
Plant innate immunity in rice: a defense against pathogen infection (2016, neutral): “to the inhibition of pathogen infection [1].”
Coping with Stresses: Roles of Calcium- and Calcium/Calmodulin-Regulated Gene Expression[W][OA] (2011, background): “In addition to many well-characterized defense signaling components (Chisholm et al., 2006; Boller and He, 2009), it is also well-established that pathogens cause substantial ion fluxes acrossmembranes.”
Impact of root exudates and plant defense signaling on bacterial communities in the rhizosphere. A review (2011, background): “Plants possess different strategies to recognize and counteract pathogen attack (Jones and Dangl 2006; Boller and He 2009).”
Regulation of primary plant metabolism during plant-pathogen interactions and its contribution to plant defense (2014, background): “Induced defenses are activated by the recognition of pathogenassociated molecular patterns (PAMPs) present on the pathogen surface (Boller and He, 2009) or by recognition of proteins (effectors) translocated by the pathogen to the host cell (Jones and Dangl, 2006; Bonardi and Dangl, 2012).”
Growth-defense tradeoffs in plants: a balancing act to optimize fitness. (2014, neutral): “While PTI is believed to provide sufficient defense against non-pathogenic microbes, pathogens have developed the ability to secrete virulence effectors into the plant cell to suppress PTI and promote disease (Boller and He, 2009; Dou and Zhou, 2012; Xin and He, 2013).”