Coping with Stresses: Roles of Calcium- and Calcium/Calmodulin-Regulated Gene Expression[W][OA]

By Anireddy S. N. Reddy, G. S. Ali, Helena Čelešnik, I. Day. The Plant Cell, 2011

714 citations recorded by the source corpus.

Abiotic and biotic stresses are major limiting factors of crop yields and cause billions of dollars of losses annually around the world. It is hoped that understanding at the molecular level how plants respond to adverse conditions and adapt to a changing environment will help in developing plants that can better cope with stresses. Acquisition of stress tolerance requires orchestration of a multitude of biochemical and physiological changes, and most of these depend on changes in gene expression. Research during the last two decades has established that different stresses cause signal-specific changes in cellular Ca2+ level, which functions as a messenger in modulating diverse physiological processes that are important for stress adaptation. In recent years, many Ca2+ and Ca2+/calmodulin (CaM) binding transcription factors (TFs) have been identified in plants. Functional analyses of some of these TFs indicate that they play key roles in stress signaling pathways. Here, we review recent progress in this area with emphasis on the roles of Ca2+- and Ca2+/CaM-regulated transcription in stress responses. We will discuss emerging paradigms in the field, highlight the areas that need further investigation, and present some promising novel high-throughput tools to address Ca2+-regulated transcriptional networks.

Subfields: Plant Science

View Paper: https://www.semanticscholar.org/paper/0fd6ee53cf61a16712e233f02f02696f046d046c

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Citations in the corpus

Comprehending crystalline β-carotene accumulation by comparing engineered cell models and the natural carotenoid-rich system of citrus (2011, neutral): “Calcium, in turn, can modulate gene transcription under abiotic and biotic stress (Reddy et al., 2011).”
Abiotic Stress in Plants and Metabolic Responses (2013, background): “General response mechanisms related to central pathways are involved in energy maintenance and include calcium signal cascades [15, 16], reactive oxygen species scavenging/signaling elements [17, 18], and energy deprivation (energy sensor protein kinase, SnRK1) signaling [19].”
Metabolic Processes During Seed Germination (2017, background): “This is accompanied with enhancement of calcium-dependent protein kinases (CDPKs), calcium/calmodulin-dependent protein kinases (CCaMKs) or phosphatases which stimulate the phosphorylation/or dephosphorylation of specific transcription factors, resulting in an increase of stress-responsive genes exp”
Heat and Drought Stresses in Crops and Approaches for Their Mitigation (2018, background): “The activated kinases or phosphatases can phosphorylate or dephosphorylate specific transcription factors (TFs), thus regulating the expression levels of stress-responsive genes (Reddy et al., 2011).”
Factors Involved in Fruit Calcium Deficiency Disorders (2012, background): “…the type and severity of the input stimulus (Dolmetsch et al. 1997), which is then decoded by downstream components of the signaling pathway, eventually leading to the specific and appropriate cellular response (Scrase-Field and Knight 2003; Dodd et al. 2010; Kudla et al. 2010; Reddy et al. 2011).”
Complexity of the Alternative Splicing Landscape in Plants[C][W][OPEN] (2013, background): “Spliceosomal Proteins in Human and Arabidopsis thaliana.”
Role of Macronutrients in Plant Growth and Acclimation: Recent Advances and Future Prospective (2014, background): “…greater role against multiple abiotic and biotic stresses, preferably drought, cold, pathogens, and wounding, as well as ethylene, auxin, MeJA, and SA (Reddy et al. 2000; Yang and Poovaiah 2000; Bouche et al. 2002; Yang and Poovaiah 2002; Galon et al. 2010; Reddy et al. 2011; Yang et al. 2013).”