Aging of skeletal muscle: a 12-yr longitudinal study.

By Walter R. Frontera, V. Hughes, Roger A. Fielding, M. Fiatarone, W. Evans, Ronenn Roubenoff. Journal of applied physiology, 2000

1,509 citations recorded by the source corpus.

Subfields: Orthopedics and Sports Medicine, Physiology

View Paper: https://www.semanticscholar.org/paper/bcacd2c38d1051b56eff3a6d51a703daed53d11d

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In Orthopedics and Sports Medicine

In Physiology

Citations in the corpus

Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia. (2011, background): “Over the age span from 20 to 80 years of age, there is approximately a 30% reduction in muscle mass and a decline in cross-sectional area of about 20% (14).”
Sarcopenia With Limited Mobility: An International Consensus (2011, background): “Loss of strength tends to track with loss of muscle mass with aging in physiological studies, although the decline in muscle strength is steeper than the decline in muscle mass.(23,24) However, interventions that increase muscle mass do not necessarily increase strength.”
Sarcopenia: current concepts. (2000, methodology): “, the force produced by a muscle per unit area, measured using computed tomography or magnetic resonance imaging) and on a cellular level (the force produced by single muscle fibers adjusted for fiber size) (14,16,17).”
Longitudinal study of muscle strength, quality, and adipose tissue infiltration. (2009, background): “For example, Frontera et al (23) observed a 20– 30% decline in strength of the knee and elbow extensors and flexors with an average ’16% loss in the CSA of the quadriceps in older men over a 12-y span.”
Age‐related differences in the dose–response relationship of muscle protein synthesis to resistance exercise in young and old men (2009, background): “Furthermore, when fibre type proportions of muscles from the same individuals at 65 years and then at 75 years were assessed, there was a decrease from ∼40–60% of type 1 content (Frontera et al. 2000).”
Skeletal Muscle: A Brief Review of Structure and Function (2014, background): “The loss of muscle mass and strength in older people is of greater magnitude in longitudinal studies when compared to crosssectional observations [52].”
Dose–Response Relationships of Resistance Training in Healthy Old Adults: A Systematic Review and Meta-Analysis (2015, background): “, crosssectional area (CSA) of the knee extensors] in elderly men with a mean age of 65 years, followed over a 12-year period [7], and (b) the effects of a 12-week RT program (three sessions/week) on the same variables of muscle strength and size in a cohort of 60- to 72-year-old men [9].”
The loss of skeletal muscle strength, mass, and quality in older adults: the health, aging and body composition study. (2006, background): “In accord with our results, Frontera and colleagues (27) reported that muscle strength at baseline and changes in muscle cross-sectional area were independent correlates of strength decline over 12 years.”