SOX2 Silencing in Glioblastoma Tumor‐Initiating Cells Causes Stop of Proliferation and Loss of Tumorigenicity

By R. Gangemi, Fabrizio Griffero, Daniela Marubbi, Marzia Perera, M. Capra, P. Malatesta, G. Ravetti, Gian Luigi Zona, A. Daga, G. Corte. Stem Cells, 2009

630 citations recorded by the source corpus.

Subfields: Cell Biology, Genetics, Oncology

View Paper: https://www.semanticscholar.org/paper/bb48e96bf9059a91976a1c690569379f614c8b92

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. Aviv Regev

In Genetics

1. Aviv Regev
2. Bradley E. Bernstein
3. A. Shalek

In Oncology

1. D. Louis

Citations in the corpus

• Reconstructing and reprogramming the tumor propagating potential of glioblastoma stem-like cells (2014, positive): “Prior studies had established SOX2 and OLIG2 as essential regulators in this context (Gangemi et al., 2009; Mehta et al., 2011).”
• Cancer stem cells in glioblastoma (2015, neutral): “Many of the transcription factors or structural proteins essential for normalNSPC function alsomark gliomaCSCs, including SOX2 (Hemmati et al. 2003), NANOG (BenPorath et al. 2008; Suva et al. 2014), OLIG2 (Ligon et al. 2007), MYC (Kim et al. 2010), MUSASHI1 (Hemmati et al. 2003), BMI1 (Hemmati et al”
• Targeting cancer stem cell pathways for cancer therapy (2020, background): “83 Sox2 also 85 These studies suggest that Sox2 promotes self-renewal and tumorigenesis and inhibits differentiation in CSCs.”