Cell Cycle via Direct Activation of the JAK-STAT Signaling Pathway in a Process Requiring PKD2

By A. Bhunia, K. Piontek, A. Boletta, Lijuan Liu, F. Qian, Peiyan Xu, F. Germino, G. Germino. 2002

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TRP Channels (2012, unknown): “development of inﬂammatory thermal hyperalgesia, it is surprising that TRPV1 diseases of the colon and ileum, and neuropeptides TRP Channels released upon sensory nerve stimulation triggered by TRPV1 activation seem to play a role in intestinal motility disorders.”
The ciliopathies: an emerging class of human genetic disorders. (2006, background): “Consistent with this hypothesis, polycystin 1 can regulate the expression of p21, a tumor suppressor that inhibits cyclin-dependent kinases leading to cell cycle arrest (11).”
Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination (2003, background): “and, most importantly, mediate mechanosensation of cilia and cell cycle contro”