Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response.

By Yan Wang, Jingshi Shen, N. Arenzana, W. Tirasophon, R. Kaufman, R. Prywes. Journal of Biological Chemistry, 2000

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XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response (2003, background): “UPRE reporter (5xATF6GL3), pCGNATF6, and pCGNAF6(1-373) were previously described (57).”
Glaucoma (2018, positive): “Increasing resistance to aqueous outflow can be achieved by scarring these pathways in the angle using a laser [1–6], by injecting microspheres or other substances in the anterior chamber [7–10], and, as described in this article, by producing scarring through injection of hypertonic saline, a scler”
Orchestrating the unfolded protein response in health and disease. (2002, background): “Analysis of a minimal UPRE motif (TGACGTGC/A) (21) uncovered a transcriptional defect in IRE1α-null mouse embryo fibroblasts that could be complemented by expression of spliced XBP1 mRNA (20), and Yoshida et al.”