Probiotic use in clinical practice: what are the risks?

By R. Boyle, R. Robins-Browne, M. Tang. American Journal of Clinical Nutrition, 2006

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How researchers see this paper

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Probiotics, prebiotics and synbiotics- a review (2015, background): “This remains the grey area which needs to be explored (Boyle et al. 2006).”
Pyrosequencing study of fecal microflora of autistic and control children. (2010, background): “Probiotic therapy to alleviate symptoms of gastrointestinal disorders has produced only slight [33,34] or no improvement of such disease states [32,35,36].”
Safety assessment of probiotics for human use (2010, background): “This is underlined by rare cases reporting the development of sepsis related to probiotic use in diseased patients.(13) The reports about negative probiotic effects clearly show that it is necessary to unravel probiotic mechanisms in the context of the intestinal barrier function and host immune fun”