Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression

By Zhigao Wang, Da-Zhi Wang, D. Hockemeyer, John R. McAnally, Alfred Nordheim, E. Olson. Nature, 2004

600 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury. (2009, background): “The results of this study reveal that SRF controls the expression of miR-143 and miR-145 in SMCs, and these miRNAs, in turn, feed back to control the expression and function of multiple components of the cytoskeleton and the SRF regulatory network (Fig. 7). In response to injury, differentiated SMCs”
Linking actin dynamics and gene transcription to drive cellular motile functions (2010, unknown): “MRTFs and TCFs display mutually exclusive interactions with SR”
MEF2: a central regulator of diverse developmental programs (2007, background): “IHH produced by prehypertrophic chondrocytes induces the expression of PTHrP, which regulates the rate at which chondrocytes undergo hypertrophy (Karaplis et al., 1994; Lanske et al., 1996; St-Jacques et al., 1999; Vortkamp et al., 1996; Weir et al., 1996).”