Influence of uterine bacterial contamination after parturition on ovarian dominant follicle selection and follicle growth and function in cattle.
By I. M. Sheldon, D. Noakes, A. Rycroft, Dirk U. Pfeiffer, H. Dobson. Reproduction, 2002
598 citations recorded by the source corpus.
First postpartum dominant follicles are preferentially selected in the ovary contralateral to the previously gravid uterine horn. The aim of the present study was to test the hypothesis that uterine bacterial contamination alters the location of ovarian follicle emergence and selection, and inhibits follicle growth and function. Swabs were collected from the uterine body lumen of cattle on days 7, 14, 21 and 28 after parturition. Bacteria were identified by aerobic and anaerobic culture; bacterial growth was scored semiquantitatively and animals were categorized into standard or high bacterial contamination categories on the basis of the number of colonies detected. Follicular growth and function were monitored by daily transrectal ultrasonography, and estimation of plasma FSH, oestradiol and progesterone concentrations. There was no effect of bacterial contamination on plasma FSH concentration profiles or emergence of the ovarian follicle wave. When uterine bacterial growth scores were high on day 7 or day 21 after parturition, fewer first (1/20 versus 15/50; P < 0.05) or second (1/11 versus 13/32; P < 0.05) dominant follicles were selected in the ipsilateral compared with the contralateral ovary, respectively. The diameter of the first dominant follicle was smaller in animals with a high day 7 bacterial score (P < 0.001), dominant follicle growth was slower (P < 0.05) and oestradiol secretion was decreased (P < 0.05). The present study provides evidence for an effect of the uterus on the ovary after parturition, whereby uterine bacteria have a contemporaneous localized effect on ovarian follicle selection and subsequent growth and function, but not on initial emergence.
Subfields: Agronomy and Crop Science, Immunology, Public Health, Environmental and Occupational Health
View Paper: https://www.semanticscholar.org/paper/b83486606d2b77c7fc39d95c2a9b2973d35f3c13
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In Agronomy and Crop Science
Citations in the corpus
- Defining postpartum uterine disease in cattle. (2006, background): “However, many spontaneous uterine infections are established within 3 weeks after parturition, before ovulation of the first dominant follicle [5,32].”
- Defining Postpartum Uterine Disease and the Mechanisms of Infection and Immunity in the Female Reproductive Tract in Cattle (2009, unknown): “E) Cows with endometritis have slower growth of dominant follicles in the ovary and lower peripheral plasma estradiol concentrations and so are less likely to ovulate [10].”
- Invited review: pathology, etiology, prevention, and treatment of fatty liver in dairy cows. (2004, background): “The delayed involution can be explained by an increased incidence, length, and severity of endometritis (Haraszti et al., 1982; Heinonen et al., 1987; Sheldon et al., 2002), which can be caused by a delayed and decreased immune response in the uterus (Zerbe et al., 2000).”