Medical progress: Heat stroke

By A. Bouchama, J. Knochel. 2002

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Scientific Opinion on Dietary Reference Values for water (2010, background): “Dehydration of more than 10% at high ambient temperatures is a serious risk for a life-threatening heat stroke with elevated body temperature, inadequate cardiac output leading to reduced perfusion of tissues and eventually to rhabdomyolysis and organ failure (Bouchama and Knochel, 2002).”
Heat Waves in the United States: Mortality Risk during Heat Waves and Effect Modification by Heat Wave Characteristics in 43 U.S. Communities (2010, result): “…al. 2008; Braga et al. 2001; Hajat et al. 2005) and of specific heat waves (Kaiser et al. 2007; Le Tertre et al. 2006) found evidence of mortality displacement, whereas experimental studies found that humans acclimatize to heat, usually within several weeks of exposure (Bouchama and Knochel 2002).”
Thermal stress and neural function: adaptive mechanisms in insect model systems (2004, background): “Furthermore, in humans heat stroke is characterized by central nervous dysfunction that results in delirium, convulsions and coma (Bouchama and Knochel, 2002).”
Ambient Temperature and Morbidity: A Review of Epidemiological Evidence (2011, background): “Over consecutive hot days without cooler nights, individuals may suffer from thermoregulatory failure, increasing the risk of illnesses (Bouchama and Knochel 2002; Parsons 2003).”