IL-6 and related cytokines as the critical lynchpins between inflammation and cancer.

By K. Taniguchi, M. Karin. Seminars in Immunology, 2014

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Macrophages and therapeutic resistance in cancer (2015, neutral): “STAT3 activation promotes neoplastic cell proliferation and survival, and multiple tumor cell lines exhibit IL-6- or STAT3-dependent chemoresistance in vitro (Taniguchi and Karin, 2014; Yu et al., 2014).”
Voluntary Running Suppresses Tumor Growth through Epinephrine- and IL-6-Dependent NK Cell Mobilization and Redistribution. (2016, neutral): “IL-6 and exercise have previously been shown to increase tumor vascularization (Taniguchi and Karin, 2014), yet we did not find any effect of IL-6 or running on CD31 and VEGF-A mRNA expression levels, nor did we detect any marked increases in capillarization in our histological analyses (data not sh”
Obesity and inflammation: the linking mechanism and the complications (2016, background): “Taniguchi and Karin [40] IL-6 Colorectal and gastric cancers”
Tumor-derived exosomes and their role in cancer progression (2016, background): “Further, CAFs co-incubated with tumor-derived exosomes acquire the capability to transform normal epithelial cells to the pre-malignant phenotype [78].”